| Long name: |
Cy7 Conjugated, PRAM1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PRAM1 |
| Specificity: |
This is a highly specific antibody against PRAM1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PRAM1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis, PRAM-1 demonstrates expression in hematopoietic tissues and lung, PRAM-1 expression is hindered by expression of PML-RAR-a, The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs, The retinoic acid-induced gene, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells, Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
PML-RAR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
PRAM1 Conjugated |
| Short name: |
Conjugated, PRAM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
alpha regulated adaptor molecule 1 (Antibody to), cyanine 7 coupled, promyelocytic leukemia-retinoic acid receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PRAM1 and IDBG-24943 and ENSG00000133246 and 84106, PRAM1 and IDBG-643837 and ENSBTAG00000021041 and 504848, Pram1 and IDBG-167526 and ENSMUSG00000032739 and 378460, lipid binding, multiple, this GO :0005515 and protein binding and molecular function this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008289 and lipid binding and molecular function this GO :0043313 and regulation of neutrophil degranulation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008289 : lipid binding, this GO :0008289 : lipid binding, PML-RARA regulated adaptor molecule 1 |
| Identity: |
30091 |
| Gene: |
PRAM1 |
More about : PRAM1 |
| Long gene name: |
PML-RARA regulated adaptor molecule 1 |
| Locus: |
19p13, 2 |
| Discovery year: |
2005-07-04 |
| GenBank acession: |
BC028012 |
| Entrez gene record: |
84106 |
| Pubmed identfication: |
11301322 15572693 |
| RefSeq identity: |
NM_032152 |
| Havana BLAST/BLAT: |
OTTHUMG00000167924 |