| Catalog number: | bs-12565R-Biotin |
|---|---|
| Price: | 402 € |
| Supplier: | abebio |
| Product name: | ABH1/ALKB Antibody, Biotin Conjugated |
| Quantity: | 1x plate of 48 wells |
| Related search: |
| Long name: | Biotin Conjugated, ABH1/ALKB Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ABH1/ALKB |
| Specificity: | This is a highly specific antibody against ABH1/ALKB |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human ABH1/ALKB |
| Gene ID number: | 8846 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | 2-oxoglutarate as a co-substrate, ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA, Deficiencies in DNA and RNA repair in mammals are associated with cancer, Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases, The enzymes act by oxidative demethylation, and molecular oxygen as the oxidizing agent, neurological disease and developmental defects, utilizing ferrous iron and alpha-ketoglutarate as cofactors, ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | ABH1, ALKB1_HUMAN, ALKBH, ALKBH1, AlkB, Alkylated DNA repair protein alkB homolog 1, Alkylation repair, Alkylation repair homolog 1, Alpha-ketoglutarate-dependent dioxygenase ABH1, DNA lyase ABH1, alkB, alkB homolog, alkylation repair homolog 1 E, coli, hABH, ABH |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | ABH1/ALKB Conjugated |
| Short name: | Conjugated, ABH1/ALKB Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, ABH1/ALKB (Antibody to) |
| Alternative technique: | antibodies |
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