| Long name: |
ABH1/ALKB Primary Polyclonal Antibody |
| Also known as: |
ABH1/ALKB PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ABH1/ALKB |
| Specificity: |
This is a highly specific antibody against ABH1/ALKB |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ABH1/ALKB |
| Gene ID number: |
8846 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
2-oxoglutarate as a co-substrate, ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA, Deficiencies in DNA and RNA repair in mammals are associated with cancer, Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases, The enzymes act by oxidative demethylation, and molecular oxygen as the oxidizing agent, neurological disease and developmental defects, utilizing ferrous iron and alpha-ketoglutarate as cofactors, ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ABH1, ALKB1_HUMAN, ALKBH, ALKBH1, AlkB, Alkylated DNA repair protein alkB homolog 1, Alkylation repair, Alkylation repair homolog 1, Alpha-ketoglutarate-dependent dioxygenase ABH1, DNA lyase ABH1, alkB, alkB homolog, alkylation repair homolog 1 E, coli, hABH, ABH |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ABH1/ALKB |
| Short name: |
ABH1/ALKB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ABH1/ALKB (Antibody to) |
| Alternative technique: |
antibodies |