| Long name: |
Biotin Conjugated, ATP6V1B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATP6V1B |
| Specificity: |
This is a highly specific antibody against ATP6V1B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ATP6V1B2/V-ATPase B2 |
| Gene ID number: |
526 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A peripheral V1 domain, In the inner ear, Like F-ATPase, Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness, Nine subunits (Aâ, The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts, The V-ATPase V1 B subunit exists as two isoforms, The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13, The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21, V-ATPase most likely operates through a rotary mechanism, V-ATPases pump protons against an electrochemical gradient, and a integral V0 domain, c, c' and c", compose V-ATPase, d, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function, thereby synthesizing ATP, which is responsible for ATP hydrolysis, which is responsible for proton translocation, while F-ATPases reverse the process, &euro, &ldquo, ) make up the V0 domain, H) make up the V1 domain and five subunits (a, Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ATP6V1 B, ATP6V1B, ATP6V1B, ATPase, ATPase H+ transporting lysosomal 56/58kDa V1 subunit B, Endomembrane proton pump 58 kDa subunit, H+ transporting, H+ transporting two sector ATPase, HO 57, HO57, V type proton ATPase subunit B, V-type proton ATPase subunit B, Vacuolar H+ ATPase 56, Vacuolar H+ ATPase 56000 subunit, Vacuolar proton pump subunit B, 000 subunit, ATP6B |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATP6V1B Conjugated |
| Short name: |
Conjugated, ATP6V1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ATP6V1B (Antibody to) |
| Alternative technique: |
antibodies |