| Long name: |
ALEXA FLUOR 488 Conjugated, ATP6V1B Polyclonal Antibody |
| Also known as: |
Anti-ATP6V1B PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATP6V1B |
| Specificity: |
This is a highly specific antibody against ATP6V1B |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATP6V1B2/V-ATPase B2 |
| Gene ID Number: |
526 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A peripheral V1 domain, In the inner ear, Like F-ATPase, Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness, Nine subunits (Aâ, The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts, The V-ATPase V1 B subunit exists as two isoforms, The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13, The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21, V-ATPase most likely operates through a rotary mechanism, V-ATPases pump protons against an electrochemical gradient, and a integral V0 domain, c, c' and c", compose V-ATPase, d, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function, thereby synthesizing ATP, which is responsible for ATP hydrolysis, which is responsible for proton translocation, while F-ATPases reverse the process, &euro, &ldquo, ) make up the V0 domain, H) make up the V1 domain and five subunits (a, Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
ATP6V1 B, ATP6V1B, ATP6V1B, ATPase, ATPase H+ transporting lysosomal 56/58kDa V1 subunit B, Endomembrane proton pump 58 kDa subunit, H+ transporting, H+ transporting two sector ATPase, HO 57, HO57, V type proton ATPase subunit B, V-type proton ATPase subunit B, Vacuolar H+ ATPase 56, Vacuolar H+ ATPase 56000 subunit, Vacuolar proton pump subunit B, 000 subunit, ATP6B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ATP6V1B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
ATP6V1B |
| Short name: |
ATP6V1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, ATP6V1B (Antibody to) |
| Alternative technique: |
antibodies |