| Long name: |
FITC Conjugated, ASL/Argininosuccinate Lyase Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASL/Argininosuccinate Lyase |
| Specificity: |
This is a highly specific antibody against ASL/Argininosuccinate Lyase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ASL/Argininosuccinate Lyase |
| Gene ID number: |
435 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ASL catalyzes the hydrolytic cleavage of argininosuccinic acid (ASA) to fumarate and arginine, ASL shares high sequence homology with the avian and reptilian eye lens protein, In addition, Localizing to the cytoplasm and existing as a homotetramer, Mutations in the gene encoding ASL leads to an accumulation of ASA in body fluids and results in Arginosuc-cinic aciduria (ASAuria), This reaction is also involved in the biosynthesis of arginine, an autosomal recessive disorder that is characterized by hyperammonemia, an essential step of the urea cycle which is crucial for the detoxification of ammonia, convulsions, d-crystallin, episodic unconsciousness and dry and brittle hair showing trich-orrhexis nodosa (weak points or nodes in the hair shaft), liver enlargement, physical and mental retardation, ASL is a member of the lyase 1 family of proteins and is predominantly expressed in the liver |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASL/Argininosuccinate Lyase Conjugated |
| Short name: |
FITC Conjugated, ASL/Argininosuccinate Lyase Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ASL/Argininosuccinate Lyase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
746 |
| Gene: |
ASL |
More about : ASL |
| Long gene name: |
argininosuccinate lyase |
| Locus: |
7q11, 21 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
435 |
| RefSeq identity: |
NM_000048 |
| Havana BLAST/BLAT: |
OTTHUMG00000022876 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |