| Long name: |
FITC Conjugated, APLF Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APLF |
| Specificity: |
This is a highly specific antibody against APLF |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human APLF |
| Gene ID number: |
200558 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
APLF interacts with XRCC1, APLF is subject to post-translational phosphorylation in response to DNA breaks, Additionally, Harlequin icthyosis, Localized to both the nucleus and the cytoplasm, The gene encoding APLF maps to human chromosome 2, XRCC4 and Ku-86 and, a rare and morbid skin deformity, an extremely rare recessive genetic disorder, is associated with mutations in the ABCA12 gene, is caused by mutations in the ALMS1 gene, is involved in single-strand and double-strand DNA break repair, via these interactions, which houses over 1, which maps to chromosome 2, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, 400 genes and comprises nearly 8% of the human genome, APLF is a 511 amino acid protein that contains one FHA doman and two C2H2type zinc fingers |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MGC47799 Xip1 ZCCHH1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APLF Conjugated |
| Short name: |
FITC Conjugated, APLF Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, APLF (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28724 |
| Gene: |
APLF |
More about : APLF |
| Long gene name: |
aprataxin and PNKP like factor |
| Synonyms gene: |
C2orf13 |
| Synonyms gene name: |
chromosome 2 open reading frame 13 |
| Synonyms name: |
CX5CX6HX5H motif containing 1 , XRCC1-interacting protein 1 zinc finger |
| Locus: |
2p13, 3 |
| Discovery year: |
2004-01-09 |
| GenBank acession: |
BC030711 |
| Entrez gene record: |
200558 |
| Pubmed identfication: |
18474613 18077224 17353262 |
| RefSeq identity: |
NM_173545 |
| Classification: |
Zinc fingers |
| Havana BLAST/BLAT: |
OTTHUMG00000129566 |