| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APLF |
| Specificity: |
This antibody reacts specifically with APLF |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human APLF |
| Gene ID: |
200558 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
APLF interacts with XRCC1, APLF is subject to post-translational phosphorylation in response to DNA breaks, Additionally, Harlequin icthyosis, Localized to both the nucleus and the cytoplasm, The gene encoding APLF maps to human chromosome 2, XRCC4 and Ku-86 and, a rare and morbid skin deformity, an extremely rare recessive genetic disorder, is associated with mutations in the ABCA12 gene, is caused by mutations in the ALMS1 gene, is involved in single-strand and double-strand DNA break repair, via these interactions, which houses over 1, which maps to chromosome 2, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, 400 genes and comprises nearly 8% of the human genome, APLF is a 511 amino acid protein that contains one FHA doman and two C2H2type zinc fingers |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC47799 Xip1 ZCCHH1 |
| Also known as: |
APLF Polyclonal Antibody |
| Other name: |
Anti-APLF Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APLF |
| Short name: |
Anti-APLF (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-APLF (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
28724 |
| Gene: |
APLF |
More about : APLF |
| Long gene name: |
aprataxin and PNKP like factor |
| Synonyms gene: |
C2orf13 |
| Synonyms gene name: |
chromosome 2 open reading frame 13 |
| Synonyms name: |
CX5CX6HX5H motif containing 1 , XRCC1-interacting protein 1 zinc finger |
| Locus: |
2p13, 3 |
| Discovery year: |
2004-01-09 |
| GenBank acession: |
BC030711 |
| Entrez gene record: |
200558 |
| Pubmed identfication: |
18474613 18077224 17353262 |
| RefSeq identity: |
NM_173545 |
| Classification: |
Zinc fingers |
| Havana BLAST/BLAT: |
OTTHUMG00000129566 |