| Long name: |
FITC Conjugated, TMEM16C/Anoctamin 3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMEM16C/Anoctamin 3 |
| Specificity: |
This is a highly specific antibody against TMEM16C/Anoctamin 3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3 |
| Gene ID number: |
63982 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Atm mutation leads to the disorder known as ataxia-telangiectasia, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, With approximately 135 million base pairs and 1, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, while Wilms' tumors, 400 genes, TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GENX-3947 DYT23 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMEM16C/Anoctamin 3 Conjugated |
| Short name: |
FITC Conjugated, TMEM16C/Anoctamin 3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TMEM16C/Anoctamin 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14004 |
| Gene: |
ANO3 |
More about : ANO3 |
| Long gene name: |
anoctamin 3 |
| Synonyms gene: |
C11orf25 TMEM16C |
| Synonyms gene name: |
chromosome 11 open reading frame 25 transmembrane protein 16C |
| Synonyms name: |
transmembrane protein 16C (eight membrane-spanning domains) |
| Locus: |
11p14, 2 |
| Discovery year: |
2000-11-28 |
| GenBank acession: |
AJ300461 |
| Entrez gene record: |
63982 |
| Pubmed identfication: |
12739008 15067359 23200863 24692353 |
| RefSeq identity: |
NM_031418 |
| Classification: |
Anoctamins |
| Havana BLAST/BLAT: |
OTTHUMG00000166096 |