| Long name: |
TMEM16C/Anoctamin 3 Primary Polyclonal Antibody |
| Also known as: |
TMEM16C/Anoctamin 3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TMEM16C/Anoctamin 3 |
| Specificity: |
This is a highly specific antibody against TMEM16C/Anoctamin 3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3 |
| Gene ID number: |
63982 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Atm mutation leads to the disorder known as ataxia-telangiectasia, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, With approximately 135 million base pairs and 1, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, while Wilms' tumors, 400 genes, TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ANO3_HUMAN, C11orf25, GENX 3947, TMEM16C, Transmembrane protein 16C, Transmembrane protein 16C eight membrane spanning domains, ANO3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMEM16C/Anoctamin 3 |
| Short name: |
TMEM16C/Anoctamin 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TMEM16C/Anoctamin 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14004 |
| Gene: |
ANO3 |
More about : ANO3 |
| Long gene name: |
anoctamin 3 |
| Synonyms gene: |
C11orf25 TMEM16C |
| Synonyms gene name: |
chromosome 11 open reading frame 25 transmembrane protein 16C |
| Synonyms: |
GENX-3947 DYT23 |
| Synonyms name: |
transmembrane protein 16C (eight membrane-spanning domains) |
| Locus: |
11p14, 2 |
| Discovery year: |
2000-11-28 |
| GenBank acession: |
AJ300461 |
| Entrez gene record: |
63982 |
| Pubmed identfication: |
12739008 15067359 23200863 24692353 |
| RefSeq identity: |
NM_031418 |
| Classification: |
Anoctamins |
| Havana BLAST/BLAT: |
OTTHUMG00000166096 |