| Long name: |
ADH5 Primary Polyclonal Antibody |
| Also known as: |
ADH5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ADH5 |
| Specificity: |
This is a highly specific antibody against ADH5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADH5 |
| Gene ID number: |
128 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ADH-3 or GSNOR, ADH5 (alcohol dehydrogenase 5 (class III)), ADH5 exists as a homodimer and, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, ADHX, Expressed ubiquitously, Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans, a product formed spontaneously between formaldehyde and glutathione, aliphatic alcohols and lipid peroxidation products, also known as FDH (formaldehyde dehydrogenase), eliminate formaldehyde, ethanol, functions as an important component of cellular metabolism, hydroxysteroids, including retinol, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases, thus, via its ability to oxidize S-hydroxymethyl-glutathione and, The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ADH5, ADHX, ADHX_HUMAN, Alcohol dehydrogenase 5, Alcohol dehydrogenase class 3, Alcohol dehydrogenase class III, Alcohol dehydrogenase class III chi polypeptide, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, FALDH, FDH, GSH-FDH, Glutathione dependent formaldehyde dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, S-hydroxymethylglutathione dehydrogenase, alcohol dehydrogenase 5 class III chi polypeptide, class III alcohol dehydrogenase 5 chi subunit, formaldehyde dehydrogenase, hydroxymethyllutathione dehydrogenase, ADH 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADH5 |
| Short name: |
ADH5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chi polypeptide (Antibody to), alcohol dehydrogenase 5 (class III) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADH-3 and ADHX and FALDH and FDH and GSH-FDH and GSNOR, ADH5 and IDBG-31067 and ENSG00000197894 and 128, ADH5 and IDBG-640968 and ENSBTAG00000016007 and 505515, Adh5 and IDBG-196598 and ENSMUSG00000028138 and 11532, S-(hydroxymethyl)glutathione dehydrogenase activity, chi polypeptide, nuclei, this GO :0001523 and retinoid metabolic process and biological process this GO :0003016 and respiratory system process and biological process this GO :0004022 and alcohol dehydrogenase (NAD) activity and molecular function this GO :0005504 and fatty acid binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0006068 and ethanol catabolic process and biological process this GO :0006069 and ethanol oxidation and biological process this GO :0007568 and aging and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009055 and electron carrier activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0018119 and peptidyl-cysteine S-nitrosylation and biological process this GO :0018467 and formaldehyde dehydrogenase activity and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045777 and positive regulation of blood pressure and biological process this GO :0046294 and formaldehyde catabolic process and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0051775 and response to redox state and biological process this GO :0051903 and S-(hydroxymethyl)glutathione dehydrogenase activity and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004022 : alcohol dehydrogenase (NAD) activity, this GO :0004022 : alcohol dehydrogenase (NAD) activity and also this GO :0005504 : fatty acid binding and also this GO :0008270 : zinc ion binding and also this GO :0009055 : electron carrier activity and also this GO :0016491 : oxidoreductase activity and also this GO :0018467 : formaldehyde dehydrogenase activity and also this GO :0042803 : protein homodimerization activity and also this GO :0051903 : S-(hydroxymethyl)glutathione dehydrogenase activity, this GO :0005504 : fatty acid binding, this GO :0008270 : zinc ion binding, this GO :0009055 : electron carrier activity, this GO :0016491 : oxidoreductase activity, this GO :0018467 : formaldehyde dehydrogenase activity, this GO :0042803 : protein homodimerization activity, this GO :0051903 : S-(hydroxymethyl)glutathione dehydrogenase activity, alcohol dehydrogenase 5 (class III) |
| Identity: |
253 |
| Gene: |
ADH5 |
More about : ADH5 |
| Long gene name: |
alcohol dehydrogenase 5 (class III), chi polypeptide |
| Synonyms gene: |
FDH |
| Synonyms gene name: |
formaldehyde dehydrogenase |
| Synonyms: |
ADH-3 ADHX GSNOR |
| Synonyms name: |
S-nitrosoglutathione reductase |
| Locus: |
4q23 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M29872 |
| Entrez gene record: |
128 |
| Pubmed identfication: |
1446828 6424546 |
| RefSeq identity: |
NM_000671 |
| Classification: |
Alcohol dehydrogenases |
| Havana BLAST/BLAT: |
OTTHUMG00000161230 |