| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Alcohol dehydrogenase 5 / ADH5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This ADH5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P11766 |
| Purity: |
Antigen affinity |
| Description: |
It has virtually no activity for ethanol oxidation, Members of this family metabolize a wide variety of substrates, The encoded protein forms a homodimer, The human genome contains several non-transcribed pseudogenes related to this gene, This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, This gene encodes a member of the alcohol dehydrogenase family, a potent irritant and sensitizing agent that causes lacrymation, a spontaneous adduct between formaldehyde and glutathione, also called Alcohol dehydrogenase 5, and contact dermatitis, and lipid peroxidation products, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, hydroxysteroids, including ethanol, is an enzyme that in humans is encoded by the ADH5 gene, other aliphatic alcohols, pharyngitis, retinol, rhinitis, Alcohol dehydrogenase class-3 |
| Immunogen: |
Amino acids K212-I374 from the human protein were used as the immunogen for the ADH5 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ADH5 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Alcohol dehydrogenase 5 / ADH5 |
| Short name: |
Alcohol dehydrogenase 5 Antibody / ADH5 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chi polypeptide, Alcohol dehydrogenase 5 (Antibody to) / alcohol dehydrogenase 5 (class III) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADH-3 and ADHX and FALDH and FDH and GSH-FDH and GSNOR, ADH5 and IDBG-31067 and ENSG00000197894 and 128, ADH5 and IDBG-640968 and ENSBTAG00000016007 and 505515, Adh5 and IDBG-196598 and ENSMUSG00000028138 and 11532, S-(hydroxymethyl)glutathione dehydrogenase activity, chi polypeptide, nuclei, this GO :0001523 and retinoid metabolic process and biological process this GO :0003016 and respiratory system process and biological process this GO :0004022 and alcohol dehydrogenase (NAD) activity and molecular function this GO :0005504 and fatty acid binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0006068 and ethanol catabolic process and biological process this GO :0006069 and ethanol oxidation and biological process this GO :0007568 and aging and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009055 and electron carrier activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0018119 and peptidyl-cysteine S-nitrosylation and biological process this GO :0018467 and formaldehyde dehydrogenase activity and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045777 and positive regulation of blood pressure and biological process this GO :0046294 and formaldehyde catabolic process and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0051775 and response to redox state and biological process this GO :0051903 and S-(hydroxymethyl)glutathione dehydrogenase activity and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004022 : alcohol dehydrogenase (NAD) activity, this GO :0004022 : alcohol dehydrogenase (NAD) activity and also this GO :0005504 : fatty acid binding and also this GO :0008270 : zinc ion binding and also this GO :0009055 : electron carrier activity and also this GO :0016491 : oxidoreductase activity and also this GO :0018467 : formaldehyde dehydrogenase activity and also this GO :0042803 : protein homodimerization activity and also this GO :0051903 : S-(hydroxymethyl)glutathione dehydrogenase activity, this GO :0005504 : fatty acid binding, this GO :0008270 : zinc ion binding, this GO :0009055 : electron carrier activity, this GO :0016491 : oxidoreductase activity, this GO :0018467 : formaldehyde dehydrogenase activity, this GO :0042803 : protein homodimerization activity, this GO :0051903 : S-(hydroxymethyl)glutathione dehydrogenase activity, alcohol dehydrogenase 5 (class III) |
| Identity: |
253 |
| Gene: |
ADH5 |
More about : ADH5 |
| Long gene name: |
alcohol dehydrogenase 5 (class III), chi polypeptide |
| Synonyms gene: |
FDH |
| Synonyms gene name: |
formaldehyde dehydrogenase |
| Synonyms: |
ADH-3 ADHX GSNOR |
| Synonyms name: |
S-nitrosoglutathione reductase |
| Locus: |
4q23 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M29872 |
| Entrez gene record: |
128 |
| Pubmed identfication: |
1446828 6424546 |
| RefSeq identity: |
NM_000671 |
| Classification: |
Alcohol dehydrogenases |
| Havana BLAST/BLAT: |
OTTHUMG00000161230 |