| Long name: |
Cy5, 5 Conjugated, DOCK4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DOCK4 |
| Specificity: |
This is a highly specific antibody against DOCK4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DOCK4 |
| Gene ID number: |
9732 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DOCK 4 contains an N-terminal SH3 domain, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, Expressed ubiquitously with highest expression in prostate, Four isoforms of DOCK 4 are expressed due to alternative splicing events, Similar to other DOCK family members, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2, glioma and colorectal carcinomas, implicated in the pathogenesis of various cancers such as ovarian, ovary and skeletal muscle, plays a role in the regulation of adherens junctions between cells, prostate, thus, via this activation, DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
FLJ34238 KIAA0716 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
DOCK4 Conjugated |
| Short name: |
Conjugated, DOCK4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, dedicator on cytokinesis 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DOCK4 and IDBG-36595 and ENSG00000128512 and 9732, DOCK4 and IDBG-632981 and ENSBTAG00000021182 and 534227, Dock4 and IDBG-136539 and ENSMUSG00000035954 and 238130, Plasma membranes, Rac GTPase binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0030165 and PDZ domain binding and molecular function this GO :0030675 and Rac GTPase activator activity and molecular function this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0032420 and stereocilium and cellular component this GO :0032421 and stereocilium bundle and cellular component this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0048365 and Rac GTPase binding and molecular function this GO :0060326 and cell chemotaxis and biological process, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0017124 : SH3 domain binding and also this GO :0030165 : PDZ domain binding and also this GO :0030675 : Rac GTPase activator activity and also this GO :0030971 : receptor tyrosine kinase binding and also this GO :0048365 : Rac GTPase binding, this GO :0005515 : protein binding, this GO :0017124 : SH3 domain binding, this GO :0030165 : PDZ domain binding, this GO :0030675 : Rac GTPase activator activity, this GO :0030971 : receptor tyrosine kinase binding, this GO :0048365 : Rac GTPase binding, dedicator of cytokinesis 4 |
| Identity: |
19192 |
| Gene: |
DOCK4 |
More about : DOCK4 |
| Long gene name: |
dedicator of cytokinesis 4 |
| Locus: |
7q31, 1 |
| Discovery year: |
2003-11-19 |
| Entrez gene record: |
9732 |
| Pubmed identfication: |
12432077 12628187 |
| RefSeq identity: |
NM_014705 |
| Havana BLAST/BLAT: |
OTTHUMG00000155077 |