| Long name: |
ALEXA FLUOR 647 Conjugated, BAMBI Polyclonal Antibody |
| Also known as: |
Anti-BAMBI PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BAMBI |
| Specificity: |
This is a highly specific antibody against BAMBI |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BAMBI |
| Gene ID Number: |
25805 |
| Swiss Prot: |
Q13145 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Pig, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain, BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines, BAMBI is expressed at high levels during odontogenesis, BAMBI transcription regulation is under the influence of beta-catenin, BMP, The BAMBI family of proteins are related to type I TGF-beta receptor family, however, smad3 and smad4, BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
NMA |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the BAMBI Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
BAMBI |
| Short name: |
BAMBI Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BAMBI and IDBG-638629 and ENSBTAG00000003045 and 530147, BAMBI and IDBG-66015 and ENSG00000095739 and 25805, Bambi and IDBG-127778 and ENSMUSG00000024232 and 68010, DNA-templated and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, NMA, Plasma membranes, this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005114 and type II transforming growth factor beta receptor binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0032092 and positive regulation of protein binding and biological process this GO :0035413 and positive regulation of catenin import into nucleus and biological process this GO :0045893 and positive regulation of transcription, this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity, this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity and also this GO :0005024 : transforming growth factor beta-activated receptor activity and also this GO :0005109 : frizzled binding and also this GO :0005114 : type II transforming growth factor beta receptor binding, this GO :0005024 : transforming growth factor beta-activated receptor activity, this GO :0005109 : frizzled binding, this GO :0005114 : type II transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) |
| Identity: |
30251 |
| Gene: |
BAMBI |
More about : BAMBI |
| Long gene name: |
BMP and activin membrane bound inhibitor |
| Synonyms gene name: |
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) |
| Locus: |
10p12, 1 |
| Discovery year: |
2004-02-04 |
| GenBank acession: |
U23070 |
| Entrez gene record: |
25805 |
| Pubmed identfication: |
8621228 19758997 |
| RefSeq identity: |
NM_012342 |
| Havana BLAST/BLAT: |
OTTHUMG00000017874 |