| Long name: |
FITC Conjugated, SUMF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SUMF1 |
| Specificity: |
This is a highly specific antibody against SUMF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SUMF1 |
| Gene ID number: |
285362 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), Expressed ubiquitously with highest expression in liver, SUMF1 exists as either a monomer, a heterogeneous disorder characterized by metachromatic leukodystrophy, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, chondrodysplasia punctata, hydrocephalus, ichthyosis, kidney and pancreas, mucopolysaccharidosis, neurologic deterioration and developmental delay, thereby playing an important role in sulfatase activity, SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FGE UNQ3037 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SUMF1 Conjugated |
| Short name: |
FITC Conjugated, SUMF1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SUMF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20376 |
| Gene: |
SUMF1 |
More about : SUMF1 |
| Long gene name: |
sulfatase modifying factor 1 |
| Locus: |
3p26, 1 |
| Discovery year: |
2004-04-30 |
| GenBank acession: |
BC017005 |
| Entrez gene record: |
285362 |
| Pubmed identfication: |
12757705 12757706 |
| RefSeq identity: |
NM_182760 |
| Havana BLAST/BLAT: |
OTTHUMG00000090269 |