| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SUMF1 |
| Specificity: |
This antibody reacts specifically with SUMF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SUMF1 |
| Gene ID: |
285362 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), Expressed ubiquitously with highest expression in liver, SUMF1 exists as either a monomer, a heterogeneous disorder characterized by metachromatic leukodystrophy, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, chondrodysplasia punctata, hydrocephalus, ichthyosis, kidney and pancreas, mucopolysaccharidosis, neurologic deterioration and developmental delay, thereby playing an important role in sulfatase activity, SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FGE UNQ3037 |
| Also known as: |
SUMF1 Polyclonal Antibody |
| Other name: |
Anti-SUMF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SUMF1 |
| Short name: |
Anti-SUMF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SUMF1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20376 |
| Gene: |
SUMF1 |
More about : SUMF1 |
| Long gene name: |
sulfatase modifying factor 1 |
| Locus: |
3p26, 1 |
| Discovery year: |
2004-04-30 |
| GenBank acession: |
BC017005 |
| Entrez gene record: |
285362 |
| Pubmed identfication: |
12757705 12757706 |
| RefSeq identity: |
NM_182760 |
| Havana BLAST/BLAT: |
OTTHUMG00000090269 |