| Long name: |
FITC Conjugated, SIX2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SIX2 |
| Specificity: |
This is a highly specific antibody against SIX2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SIX2 |
| Gene ID number: |
10736 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It has been demonstrated that alterations to homeobox-containing genes may result in cancer, Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, Six1 expression has been shown to be absent or low in normal adult tissues, Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint, Six2, Six2 is highly expressed in fetal tissues but expression is limited in adult tissues, Six4 (AREC3) and Six5 bind to the same DNA sequence, although it is expressed in several tumor types, including breast carcinoma, indicating that they may regulate the same target genes, such as myogenin, The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SIX2 Conjugated |
| Short name: |
FITC Conjugated, SIX2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SIX2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10888 |
| Gene: |
SIX2 |
More about : SIX2 |
| Long gene name: |
SIX homeobox 2 |
| Synonyms gene name: |
sine oculis homeobox (Drosophila) homolog 2 sine oculis homeobox homolog 2 (Drosophila) |
| Locus: |
2p21 |
| Discovery year: |
1999-04-15 |
| GenBank acession: |
AF136939 |
| Entrez gene record: |
10736 |
| Classification: |
SINE class homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000152421 |