| Long name: |
ALEXA FLUOR 647 Conjugated, RASSF1 Polyclonal Antibody |
| Also known as: |
Anti-RASSF1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RASSF1 |
| Specificity: |
This is a highly specific antibody against RASSF1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
150-195/340 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RASSF1 |
| Gene ID Number: |
11186 |
| Swiss Prot: |
Q9NS23 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
APC, DAXX and USP7, Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein, Isoform A disrupts interactions among MDM2, Isoform A interacts with CDC2, Isoform C has been shown not to perform these roles, Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation, Required for death receptor-dependent apoptosis, When associated with MOAP1, an activator of the anaphase-promoting complex, no function has been identified for this isoform, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF1 stimulation, resulting in the inhibition of APC activity and mitotic progression, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage, Potential tumor suppressor |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
NORE2A REH3P21 RDA32 123F2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the RASSF1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
RASSF1 |
| Short name: |
RASSF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, RASSF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9882 |
| Gene: |
RASSF1 |
More about : RASSF1 |
| Long gene name: |
Ras association domain family member 1 |
| Synonyms gene name: |
Ras association (RalGDS/AF-6) domain family member 1 |
| Locus: |
3p21, 31 |
| Discovery year: |
2000-05-30 |
| GenBank acession: |
AF132675 |
| Entrez gene record: |
11186 |
| Classification: |
Ras association domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000149958 |