| Long name: |
Cy3 Conjugated, CPA3/MC-CPA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CPA3/MC-CPA |
| Specificity: |
This is a highly specific antibody against CPA3/MC-CPA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CPA3/MC-CPA |
| Gene ID number: |
1359 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CPA3, MC-CPA is stored as an active enzyme in the granule and is released, MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues, Mast cell carboxypeptidase A (MC-CPA), The MC-CPA gene, The optimum pH of MC-CPA is between neutral and basic, a part of the peptidase M14 family, along with other inflammatory mediators, along with trytases and chymases, depending upon the substrate, is a highly conserved metalloprotease localized to the secretory granules, resides on chromosome 3 and contains 11 exons, upon mast cell degranulation, Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Properties: |
1 of the CPA3/MC-CPA Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CPA3/MC-CPA Conjugated |
| Short name: |
Conjugated, CPA3/MC-CPA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, carboxypeptidase A3 (mast cell)/MC-CPA (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CPA3 and IDBG-60396 and ENSG00000163751 and 1359, CPA3 and IDBG-637892 and ENSBTAG00000015008 and 528454, Cpa3 and IDBG-133537 and ENSMUSG00000001865 and 12873, Extracellular, MC-CPA, this GO :0002002 and regulation of angiotensin levels in blood and biological process this GO :0002003 and angiotensin maturation and biological process this GO :0004180 and carboxypeptidase activity and molecular function this GO :0004181 and metallocarboxypeptidase activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006508 and proteolysis and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0030133 and transport vesicle and cellular component this GO :0030141 and secretory granule and cellular component this GO :0044267 and cellular protein metabolic process and biological process, this GO :0004180 : carboxypeptidase activity, this GO :0004180 : carboxypeptidase activity and also this GO :0004181 : metallocarboxypeptidase activity and also this GO :0008233 : peptidase activity and also this GO :0008270 : zinc ion binding, this GO :0004181 : metallocarboxypeptidase activity, this GO :0008233 : peptidase activity, this GO :0008270 : zinc ion binding, zinc ion binding, carboxypeptidase A3 (mast cell) |
| Identity: |
2298 |
| Gene: |
CPA3 |
More about : CPA3 |
| Long gene name: |
carboxypeptidase A3 |
| Synonyms gene name: |
carboxypeptidase A3 (mast cell) |
| Synonyms name: |
mast cell carboxypeptidase A tissue carboxypeptidase A |
| Locus: |
3q24 |
| Discovery year: |
1990-06-13 |
| Entrez gene record: |
1359 |
| RefSeq identity: |
NM_001870 |
| Classification: |
Carboxypeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000159526 |