| Long name: |
ALEXA FLUOR 488 Conjugated, CDON Polyclonal Antibody |
| Also known as: |
Anti-CDON PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CDON |
| Specificity: |
This is a highly specific antibody against CDON |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDON |
| Gene ID Number: |
50937 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation, CDO and BOC participate in a positive feedback loop with MyoD, CDO is a component of a cell-surface receptor complex which also contains BOC, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells, NEO1, The 1, The human protein contains 1, Together, a 25 residue membrane-spanning region, a myogenic transcription factor, five Ig V-like repeats, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch, 225 amino acid residues and shares significant homology with the domain structures of the rat protein, 242 amino acid rat CDO protein has a 24 residue signal sequence, Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
ORCAM CDO CDON1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CDON Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CDON |
| Short name: |
CDON Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Cdon homolog (mouse) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDON and IDBG-642728 and ENSBTAG00000009315 and 536011, CDON and IDBG-75707 and ENSG00000064309 and 50937, Cdon and IDBG-148540 and ENSMUSG00000038119 and 57810, Extracellular, protein binding, this GO :0001708 and cell fate specification and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002088 and lens development in camera-type eye and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007520 and myoblast fusion and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010172 and embryonic body morphogenesis and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0021987 and cerebral cortex development and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042692 and muscle cell differentiation and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043497 and regulation of protein heterodimerization activity and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048598 and embryonic morphogenesis and biological process this GO :0048643 and positive regulation of skeletal muscle tissue development and biological process this GO :0051057 and positive regulation of small GTPase mediated signal transduction and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0060059 and embryonic retina morphogenesis in camera-type eye and biological process this GO :2000179 and positive regulation of neural precursor cell proliferation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, Cdon homolog (mouse) |
| Identity: |
17104 |
| Gene: |
CDON |
More about : CDON |
| Long gene name: |
cell adhesion associated, oncogene regulated |
| Synonyms gene name: |
Cdon homolog (mouse) |
| Synonyms name: |
cell adhesion molecule-related/down-regulated by oncogenes |
| Locus: |
11q24, 2 |
| Discovery year: |
2001-11-02 |
| GenBank acession: |
AF004841 |
| Entrez gene record: |
50937 |
| Pubmed identfication: |
9214393 |
| RefSeq identity: |
NM_016952 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165862 |