| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDON |
| Specificity: |
This antibody reacts specifically with CDON |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CDON |
| Gene ID: |
50937 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation, CDO and BOC participate in a positive feedback loop with MyoD, CDO is a component of a cell-surface receptor complex which also contains BOC, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells, NEO1, The 1, The human protein contains 1, Together, a 25 residue membrane-spanning region, a myogenic transcription factor, five Ig V-like repeats, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch, 225 amino acid residues and shares significant homology with the domain structures of the rat protein, 242 amino acid rat CDO protein has a 24 residue signal sequence, Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ORCAM CDO CDON1 |
| Also known as: |
CDON Polyclonal Antibody |
| Other name: |
Anti-CDON Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDON |
| Short name: |
Anti-CDON (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cdon homolog (mouse) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CDON and IDBG-642728 and ENSBTAG00000009315 and 536011, CDON and IDBG-75707 and ENSG00000064309 and 50937, Cdon and IDBG-148540 and ENSMUSG00000038119 and 57810, Extracellular, protein binding, this GO :0001708 and cell fate specification and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002088 and lens development in camera-type eye and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007520 and myoblast fusion and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010172 and embryonic body morphogenesis and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0021987 and cerebral cortex development and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042692 and muscle cell differentiation and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043497 and regulation of protein heterodimerization activity and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048598 and embryonic morphogenesis and biological process this GO :0048643 and positive regulation of skeletal muscle tissue development and biological process this GO :0051057 and positive regulation of small GTPase mediated signal transduction and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0060059 and embryonic retina morphogenesis in camera-type eye and biological process this GO :2000179 and positive regulation of neural precursor cell proliferation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, Cdon homolog (mouse) |
| Identity: |
17104 |
| Gene: |
CDON |
More about : CDON |
| Long gene name: |
cell adhesion associated, oncogene regulated |
| Synonyms gene name: |
Cdon homolog (mouse) |
| Synonyms name: |
cell adhesion molecule-related/down-regulated by oncogenes |
| Locus: |
11q24, 2 |
| Discovery year: |
2001-11-02 |
| GenBank acession: |
AF004841 |
| Entrez gene record: |
50937 |
| Pubmed identfication: |
9214393 |
| RefSeq identity: |
NM_016952 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165862 |