| Long name: |
Cy3 Conjugated, CYB5R3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CYB5R3 |
| Specificity: |
This is a highly specific antibody against CYB5R3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CYB5R3 |
| Gene ID number: |
1727 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A serine residue at position 117 seems to only be found in persons of African origin, Asians, CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms, CYB5R3 is involved in the desaturation and elongation of fatty acids, Defects in CYB5R3 are the cause of hereditary methemoglobinemia (HM), Indo-Aryans or Arabs, Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, It is not found in Caucasians, The allele frequency is 0, There are three forms of this disease: type 1 (HM1), This difference seems to have no effect on the enzyme activity, Type 2 is a severe form accompanied by mental retardation and neurological impairment, and type 3 (HM3), cholesterol biosynthesis, drug metabolism and, in erythrocytes, in which the enzyme is completely deficient, in which the enzyme is only deficient in erythrocytes with a mild cyanosis, methemoglobin reduction, type 2 (HM2), where the deficiency is seen in all blood cells, while isoform 2 is the soluble form found in erythrocytes, 23 in African Americans, CYB5R3 is a 301 amino acid protein encoded by the human gene CYB5R3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Properties: |
1 of the CYB5R3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CYB5R3 Conjugated |
| Short name: |
Conjugated, CYB5R3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, CYB5R3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2873 |
| Gene: |
CYB5R3 |
More about : CYB5R3 |
| Long gene name: |
cytochrome b5 reductase 3 |
| Synonyms gene: |
DIA1 |
| Synonyms gene name: |
diaphorase (NADH) (cytochrome b-5 reductase) |
| Synonyms name: |
NADH-cytochrome b5 reductase 3 |
| Locus: |
22q13, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M16461 |
| Entrez gene record: |
1727 |
| Pubmed identfication: |
2479590 3268037 |
| Havana BLAST/BLAT: |
OTTHUMG00000150745 |