| Long name: |
ALEXA FLUOR 594 Conjugated, SHC2/Sck Polyclonal Antibody |
| Also known as: |
Anti-SHC2/Sck PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHC2/Sck |
| Specificity: |
This is a highly specific antibody against SHC2/Sck |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHC2/Sck |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Human Sck transcripts are present at high levels in liver, In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6), Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2, pancreas, prostate and ovary (4, 3), 5), 8), Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SLI SCK SHCB |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
SHC2/Sck |
| Short name: |
SHC2/Sck Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, SHC2/Sck (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29869 |
| Gene: |
SHC2 |
More about : SHC2 |
| Long gene name: |
SHC adaptor protein 2 |
| Synonyms gene name: |
SHC (Src homology 2 domain containing) transforming protein 2 |
| Synonyms name: |
neuronal Shc adaptor homolog |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-03-18 |
| GenBank acession: |
AB001451 |
| Entrez gene record: |
25759 |
| Pubmed identfication: |
7527937 9507002 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180545 |