| Catalog number: | bs-12144R-A555 |
|---|---|
| Price: | 2243 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | SHC2/Sck Antibody, ALEXA FLUOR 555 |
| Quantity: | 1000ug |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, SHC2/Sck Polyclonal Antibody |
|---|---|
| Also known as: | Anti-SHC2/Sck PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | SHC2/Sck |
| Specificity: | This is a highly specific antibody against SHC2/Sck |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHC2/Sck |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Human Sck transcripts are present at high levels in liver, In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6), Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2, pancreas, prostate and ovary (4, 3), 5), 8), Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1) |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | SLI SCK SHCB |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | SHC2/Sck |
| Short name: | SHC2/Sck Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, SHC2/Sck (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 29869 |
| Gene: | SHC2 | More about : SHC2 |
| Long gene name: | SHC adaptor protein 2 |
| Synonyms gene name: | SHC (Src homology 2 domain containing) transforming protein 2 |
| Synonyms name: | neuronal Shc adaptor homolog |
| Locus: | 19p13, 3 |
| Discovery year: | 2004-03-18 |
| GenBank acession: | AB001451 |
| Entrez gene record: | 25759 |
| Pubmed identfication: | 7527937 9507002 |
| Classification: | SH2 domain containing |
| Havana BLAST/BLAT: | OTTHUMG00000180545 |
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