| Long name: |
ALEXA FLUOR 488 Conjugated, APXL Polyclonal Antibody |
| Also known as: |
Anti-APXL PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APXL |
| Specificity: |
This is a highly specific antibody against APXL |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APXL |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
APXL interacts with F-Actin and is thought to mediate endothelial cell morphology during cell spreading, APXL is expressed in kidney, Containing one ASD1 domain, In conjunction with chromosome Y, The gene encoding APXL maps to human chromosome X, There are a number of conditions related to an abnormal number and combination of sex chromosomes, Tubulin redistribution, brain, chromosome X is responsible for sex determination, color blindness, hemophilia and Duchenne muscular dystrophy, including the cytoplasm, lung, one ASD2 domain and one PDZ domain, pancreas and placenta and is overexpressed in melanomas, possibly regulating melanosome biogenesis and inducing Î, some of which include Turner's syndrome, suggesting a role in tumor transformation and metastasis, the cell junction and the apical cell membrane, the cytoskeleton, which contains nearly 153 million base pairs and houses over 1, ³, 000 genes, 616 amino acid protein that localizes to a variety of locations within the cell, APXL is a 1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the APXL Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
APXL |
| Short name: |
APXL Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, APXL (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
630 |
| Gene: |
SHROOM2 |
More about : SHROOM2 |
| Long gene name: |
shroom family member 2 |
| Synonyms gene: |
APXL |
| Synonyms gene name: |
Xenopus laevis-like apical protein-like (Xenopus laevis) , apical protein |
| Locus: |
Xp22, 2 |
| Discovery year: |
1995-06-13 |
| GenBank acession: |
X83543 |
| Entrez gene record: |
357 |
| Pubmed identfication: |
7795590 16615870 |
| RefSeq identity: |
NM_001649 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000021121 |
| Locus Specific Databases: |
Mental Retardation database |