| Long name: |
APXL Primary Polyclonal Antibody |
| Also known as: |
APXL PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APXL |
| Specificity: |
This is a highly specific antibody against APXL |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APXL |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
APXL interacts with F-Actin and is thought to mediate endothelial cell morphology during cell spreading, APXL is expressed in kidney, Containing one ASD1 domain, In conjunction with chromosome Y, The gene encoding APXL maps to human chromosome X, There are a number of conditions related to an abnormal number and combination of sex chromosomes, Tubulin redistribution, brain, chromosome X is responsible for sex determination, color blindness, hemophilia and Duchenne muscular dystrophy, including the cytoplasm, lung, one ASD2 domain and one PDZ domain, pancreas and placenta and is overexpressed in melanomas, possibly regulating melanosome biogenesis and inducing Î, some of which include Turner's syndrome, suggesting a role in tumor transformation and metastasis, the cell junction and the apical cell membrane, the cytoskeleton, which contains nearly 153 million base pairs and houses over 1, ³, 000 genes, 616 amino acid protein that localizes to a variety of locations within the cell, APXL is a 1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APX homolog of Xenopus, Apical like protein APXL protein, Apical protein Xenopus laevis like, Apical-like protein, C630003H05Rik, DKFZp781J074, FLJ39277, HSAPXL, Liver regeneration-related protein LRRG167, Protein Apxl, Protein Shroom2, SHRM2_HUMAN, SHROOM 2, Shrm2, Shroom family member 2, Xenopus laevis-like, apical protein, apical protein of Xenopus-like, apical protein-like, apical protein-like Xenopus laevis, shroom2, Apical like protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APXL |
| Short name: |
APXL Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
APXL (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
630 |
| Gene: |
SHROOM2 |
More about : SHROOM2 |
| Long gene name: |
shroom family member 2 |
| Synonyms gene: |
APXL |
| Synonyms gene name: |
Xenopus laevis-like apical protein-like (Xenopus laevis) , apical protein |
| Locus: |
Xp22, 2 |
| Discovery year: |
1995-06-13 |
| GenBank acession: |
X83543 |
| Entrez gene record: |
357 |
| Pubmed identfication: |
7795590 16615870 |
| RefSeq identity: |
NM_001649 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000021121 |
| Locus Specific Databases: |
Mental Retardation database |