| Long name: |
FITC Conjugated, TRPV3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRPV3 |
| Specificity: |
This is a highly specific antibody against TRPV3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TRPV3 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Human TRPV3 is expressed in skin, In addition, It is abundantly expressed in kidney, TRPV3 associates with VR-1 and may modulate VR-1 activity, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1, TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine, The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, an N-linked glycosylation site and three ankyrin repeat regions, and at lower levels in testis, brain, capsaicin-insensitive TRPV3 is expressed at warm temperatures, colon and rectum, dorsal root ganglion, expression increases in response to noxious temperatures, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, jejunum and pancreas, multiple potential phosphorylation sites, placenta, prostate, spinal cord and brain, the 5â, the thermal-sensitive, tongue, trigeminal ganglion, &euro, &trade, -flanking region of TRPV5 contains four putative vitamin D3-responsive elements, Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
VRL3 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRPV3 Conjugated |
| Short name: |
FITC Conjugated, TRPV3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TRPV3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18084 |
| Gene: |
TRPV3 |
More about : TRPV3 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 3 |
| Synonyms gene name: |
member 3 , subfamily V, transient receptor potential cation channel |
| Locus: |
17p13, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF514998 |
| Entrez gene record: |
162514 |
| Pubmed identfication: |
12016205 12077606 16382100 |
| RefSeq identity: |
NM_145068 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000090695 |