| Long name: |
Biotin Conjugated, TRPV3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRPV3 |
| Specificity: |
This is a highly specific antibody against TRPV3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TRPV3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Human TRPV3 is expressed in skin, In addition, It is abundantly expressed in kidney, TRPV3 associates with VR-1 and may modulate VR-1 activity, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1, TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine, The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, an N-linked glycosylation site and three ankyrin repeat regions, and at lower levels in testis, brain, capsaicin-insensitive TRPV3 is expressed at warm temperatures, colon and rectum, dorsal root ganglion, expression increases in response to noxious temperatures, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, jejunum and pancreas, multiple potential phosphorylation sites, placenta, prostate, spinal cord and brain, the 5â, the thermal-sensitive, tongue, trigeminal ganglion, &euro, &trade, -flanking region of TRPV5 contains four putative vitamin D3-responsive elements, Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
VRL3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRPV3 Conjugated |
| Short name: |
Conjugated, TRPV3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TRPV3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18084 |
| Gene: |
TRPV3 |
More about : TRPV3 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 3 |
| Synonyms gene name: |
member 3 , subfamily V, transient receptor potential cation channel |
| Locus: |
17p13, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF514998 |
| Entrez gene record: |
162514 |
| Pubmed identfication: |
12016205 12077606 16382100 |
| RefSeq identity: |
NM_145068 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000090695 |