CAPON Antibody, ALEXA FLUOR 594

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Catalog number: bs-11987R-A594
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: CAPON Antibody, ALEXA FLUOR 594
Quantity: 100ul
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More details :

Long name: ALEXA FLUOR 594 Conjugated, CAPON Polyclonal Antibody
Also known as: Anti-CAPON PAb ALEXA FLUOR 594
Category: Conjugated Primary Antibodies
Conjugated with: 594, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: CAPON
Specificity: This is a highly specific antibody against CAPON
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CAPON
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, The association of nNOS with PSD95 or PSD93 is regulated by CAPON, The carboxy terminus of CAPON binds to the PDZ domain, These proteins facilitate the transport of nNOS to the plasma membrane, and sequesters nNOS in the cytosol, but not to endothelial NOS or inducible NOS, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain, where it is catalytically activated by NMDA-receptor mediated calcium channels, CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS)
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 590nm/617nm
Synonyms: KIAA0464 CAPON
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: 594, ALEXA FLUOR®, Alexa Fluor
Conjugated: Alexa conjugate 1
Gene target: CAPON
Short name: CAPON Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 594
Alternative name: ALEXA FLUOR 594, CAPON (Antibody to)
Alternative technique: antibodies
Identity: 16859
Gene: NOS1AP | More about : NOS1AP
Long gene name: nitric oxide synthase 1 adaptor protein
Synonyms gene name: nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms name: C-terminal PDZ domain ligand of neuronal nitric oxide synthase
Locus: 1q23, 3
Discovery year: 2005-06-15
GenBank acession: AB007933
Entrez gene record: 9722
Pubmed identfication: 9455484 9459447
RefSeq identity: NM_014697
Havana BLAST/BLAT: OTTHUMG00000024049

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