| Long name: |
Biotin Conjugated, NCS1/Frequenin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NCS1/Frequenin |
| Specificity: |
This is a highly specific antibody against NCS1/Frequenin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NCS1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It is also expressed in glial cells and in neuroendocrine bovine adrenal chromaffin and PC12 cells, NCS-1 also functions in the voltage-independent autocrine pathway that negatively regulates non-L-type Ca++ channels, NCS-1 is a regulatory protein involved in Ca++-dependent exocytosis of synaptic vesicles and dense core granules, NCS-1 is localized to neuronal cell bodies and axons throughout the brain and spinal cord, also designated frequenin) belongs to a highly conserved family of EF-hand-containing Ca++-binding proteins expressed mainly in neurons, NCS-1 (for neuronal calcium sensor-1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NCS-1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NCS1/Frequenin Conjugated |
| Short name: |
Conjugated, NCS1/Frequenin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, neuronal calcium sensor 1/Frequenin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Cell surfaces, FLUP and FREQ, NCS1 and IDBG-89459 and ENSG00000107130 and 23413, Ncs1 and IDBG-157707 and ENSMUSG00000062661 and 14299, protein kinase binding, this GO :0000287 and magnesium ion binding and molecular function this GO :0005245 and voltage-gated calcium channel activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010975 and regulation of neuron projection development and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031045 and dense core granule and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032580 and this GO lgi cisterna membrane and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045921 and positive regulation of exocytosis and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070588 and calcium ion transmembrane transport and biological process, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0005245 : voltage-gated calcium channel activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding, this GO :0005245 : voltage-gated calcium channel activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, 40187 and IDBG-639872 and ENSBTAG00000008726 and 526544, neuronal calcium sensor 1 |
| Identity: |
3953 |
| Gene: |
NCS1 |
More about : NCS1 |
| Long gene name: |
neuronal calcium sensor 1 |
| Synonyms gene: |
FREQ |
| Synonyms gene name: |
frequenin (Drosophila) homolog frequenin homolog (Drosophila) |
| Locus: |
9q34, 11 |
| Discovery year: |
2000-06-09 |
| GenBank acession: |
AF186409 |
| Entrez gene record: |
23413 |
| Pubmed identfication: |
11092894 26705828 |
| RefSeq identity: |
NM_014286 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020801 |