| Long name: |
ALEXA FLUOR 555 Conjugated, NUMBL Polyclonal Antibody |
| Also known as: |
Anti-NUMBL PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NUMBL |
| Specificity: |
This is a highly specific antibody against NUMBL |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NUMBL |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CAG3A, CTG3a, Expressed at high levels in developing brain tissue, In mice, LNX1 and Notch 1, NBL, NUMBLIKE or TNRC23, NumbL (NUMB-like protein), NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, a signaling adapter protein with two protein-protein interaction domains, also known as Numb-R, deletion of the NumbL gene is associated with early embryonic death, including Eps15, is a 609 amino acid cytoplasmic protein that, is thought to play a role in cell fate, like NUMB, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR), neuronal cell fate decisions are directed by NUMB, possibly associating with Eps15 and Notch 1, suggesting an essential role for NumbL in early development, In Drosophila |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
NUMB-R CTG3a CAG3A TNRC23 NUMBR NUMBLIKE |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
NUMBL |
| Short name: |
NUMBL Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, numb homolog (Drosophila)-like (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CAG3A and CTG3a and NBL and NUMB-R and NUMBLIKE and NUMBR and TNRC23, Cytoplasm, NUMBL and IDBG-52025 and ENSG00000105245 and 9253, NUMBL and IDBG-638153 and ENSBTAG00000019461 and 510973, Numbl and IDBG-160322 and ENSMUSG00000063160 and 18223, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007399 and nervous system development and biological process this GO :0007405 and neuroblast proliferation and biological process this GO :0007409 and axonogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019538 and protein metabolic process and biological process this GO :0021670 and lateral ventricle development and biological process this GO :0021849 and neuroblast division in subventricular zone and biological process this GO :0030900 and forebrain development and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045087 and innate immune response and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0050775 and positive regulation of dendrite morphogenesis and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, numb homolog (Drosophila)-like |
| Identity: |
8061 |
| Gene: |
NUMBL |
More about : NUMBL |
| Long gene name: |
NUMB like, endocytic adaptor protein |
| Synonyms gene name: |
numb (Drosophila) homolog-like |
| Locus: |
19q13, 2 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
AF015401 |
| Entrez gene record: |
9253 |
| Pubmed identfication: |
9225980 9303539 |
| RefSeq identity: |
NM_004756 |
| Classification: |
Trinucleotide repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182627 |