| Long name: |
ALEXA FLUOR 488 Conjugated, Six3 Polyclonal Antibody |
| Also known as: |
Anti-Six3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Six3 |
| Specificity: |
This is a highly specific antibody against Six3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Six3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
At 20 weeks of gestation, Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain, Six3 maps to human chromosome 2p16-p21, The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region, and is maintained in the eye throughout the entire period of fetal development, between genetic markers D2S119 and D2S288, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer, The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
SIX3OS |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Six3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Six3 |
| Short name: |
Six3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Six3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
40532 |
| Gene: |
SIX3-AS1 |
More about : SIX3-AS1 |
| Long gene name: |
SIX3 antisense RNA 1 |
| Synonyms gene name: |
SIX3 antisense RNA 1 (non-protein coding) |
| Locus: |
2p21 |
| Discovery year: |
2012-05-01 |
| GenBank acession: |
BM690547 BM663835 |
| Entrez gene record: |
100506108 |
| Pubmed identfication: |
15703187 |
| RefSeq identity: |
NR_103785 |
| Havana BLAST/BLAT: |
OTTHUMG00000152423 |