| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Six3 |
| Specificity: |
This antibody reacts specifically with Six3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Six3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
At 20 weeks of gestation, Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain, Six3 maps to human chromosome 2p16-p21, The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region, and is maintained in the eye throughout the entire period of fetal development, between genetic markers D2S119 and D2S288, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer, The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SIX3OS |
| Also known as: |
Six3 Polyclonal Antibody |
| Other name: |
Anti-Six3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Six3 |
| Short name: |
Anti-Six3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Six3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
40532 |
| Gene: |
SIX3-AS1 |
More about : SIX3-AS1 |
| Long gene name: |
SIX3 antisense RNA 1 |
| Synonyms gene name: |
SIX3 antisense RNA 1 (non-protein coding) |
| Locus: |
2p21 |
| Discovery year: |
2012-05-01 |
| GenBank acession: |
BM690547 BM663835 |
| Entrez gene record: |
100506108 |
| Pubmed identfication: |
15703187 |
| RefSeq identity: |
NR_103785 |
| Havana BLAST/BLAT: |
OTTHUMG00000152423 |