| Long name: |
Biotin Conjugated, SLITRK2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLITRK2 |
| Specificity: |
This is a highly specific antibody against SLITRK2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human SLITRK2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth, Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events, Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia, suggesting that it suppresses neurite outgrowth, with highest levels found in adult cerebral cortex, SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIAA1854 CXorf2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLITRK2 Conjugated |
| Short name: |
Conjugated, SLITRK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, SLITRK2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13449 |
| Gene: |
SLITRK2 |
More about : SLITRK2 |
| Long gene name: |
SLIT and NTRK like family member 2 |
| Synonyms gene: |
SLITL1 |
| Synonyms gene name: |
member 2 , slit-like 1 (Drosophila) SLIT and NTRK-like family |
| Locus: |
Xq27, 3 |
| Discovery year: |
2004-03-11 |
| GenBank acession: |
Y19205 |
| Entrez gene record: |
84631 |
| Pubmed identfication: |
11347906 14557068 |
| RefSeq identity: |
NM_032539 |
| Havana BLAST/BLAT: |
OTTHUMG00000022595 |
| Locus Specific Databases: |
Mental Retardation database |