| Long name: |
ALEXA FLUOR 555 Conjugated, SLITRK2 Polyclonal Antibody |
| Also known as: |
Anti-SLITRK2 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLITRK2 |
| Specificity: |
This is a highly specific antibody against SLITRK2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLITRK2 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth, Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events, Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia, suggesting that it suppresses neurite outgrowth, with highest levels found in adult cerebral cortex, SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
KIAA1854 CXorf2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
SLITRK2 |
| Short name: |
SLITRK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, SLITRK2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13449 |
| Gene: |
SLITRK2 |
More about : SLITRK2 |
| Long gene name: |
SLIT and NTRK like family member 2 |
| Synonyms gene: |
SLITL1 |
| Synonyms gene name: |
member 2 , slit-like 1 (Drosophila) SLIT and NTRK-like family |
| Locus: |
Xq27, 3 |
| Discovery year: |
2004-03-11 |
| GenBank acession: |
Y19205 |
| Entrez gene record: |
84631 |
| Pubmed identfication: |
11347906 14557068 |
| RefSeq identity: |
NM_032539 |
| Havana BLAST/BLAT: |
OTTHUMG00000022595 |
| Locus Specific Databases: |
Mental Retardation database |