| Long name: |
Radical Fringe Primary Polyclonal Antibody |
| Also known as: |
Radical Fringe PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Radical Fringe |
| Specificity: |
This is a highly specific antibody against Radical Fringe |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Radical Fringe |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Each mammalian Fringe displays different patterns of expression, Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation, Lunatic Fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock, Manic, Manic Fringe, Playing a key role in the development of the limb bud, Radical Fringe, Radical Fringe transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor, Radical and Lunatic Fringe, a protein involved in development, also involved in somatic development, also known as Beta-1, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice, have been identified as proteins related to Drosophila Fringe, is a 331 amino acid single-pass type II membrane protein that localizes to the membrane of the Golgi apparatus, though all are expressed in the mouse embryo as well as in many adult tissues, 3-N-acetylglucosaminyltransferase Radical Fringe, Three mammalian fringe family members |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Beta-1, Beta-1, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, RFNG, RFNG_HUMAN, 3-N-acetylglucosaminyltransferase radical fringe, 3-N-acetylglucosaminyltransferase radical fringe |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Radical Fringe |
| Short name: |
Radical Fringe Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Radical Fringe (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9974 |
| Gene: |
RFNG |
More about : RFNG |
| Long gene name: |
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| Synonyms gene name: |
radical fringe (Drosophila) homolog radical fringe homolog (Drosophila) |
| Locus: |
17q25, 3 |
| Discovery year: |
1997-11-07 |
| GenBank acession: |
BC069034 |
| Entrez gene record: |
5986 |
| Pubmed identfication: |
9187150 |
| RefSeq identity: |
NM_002917 |
| Classification: |
Beta 3-glycosyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000178512 |