| Long name: |
HRP Conjugated, NOTUM Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NOTUM |
| Specificity: |
This is a highly specific antibody against NOTUM |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NOTUM |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BRCA1 is directly involved in DNA repair, Encoding more than 1, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene that encodes Notum consists of approximately 9, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, chromosome 17 comprises over 2, colon, namely, p53 and BRCA1, prostate gland and fallopian tubes, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, 200 genes, 3, 334 bases and maps to human chromosome 17q25, 5% of the human genome, Notum is a 496 amino acid secreted protein that belongs to the pectinacetylesterase family and may deacetylate GlcNAc residues on cell surface glycans |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
NOTUM Conjugated |
| Short name: |
Conjugated, NOTUM Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, NOTUM (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
27106 |
| Gene: |
NOTUM |
More about : NOTUM |
| Long gene name: |
NOTUM, palmitoleoyl-protein carboxylesterase |
| Synonyms gene name: |
notum pectinacetylesterase homolog (Drosophila) |
| Synonyms name: |
[Wnt protein] O-palmitoleoyl-L-serine hydrolase |
| Locus: |
17q25, 3 |
| Discovery year: |
2005-11-22 |
| GenBank acession: |
BC060882 |
| Entrez gene record: |
147111 |
| Pubmed identfication: |
25731175 |
| RefSeq identity: |
NM_178493 |
| Havana BLAST/BLAT: |
OTTHUMG00000154416 |