| Long name: |
ALEXA FLUOR 594 Conjugated, LIM kinase 1 + 2 Polyclonal Antibody |
| Also known as: |
Anti-LIM kinase 1 + 2 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LIM kinase 1 + 2 |
| Specificity: |
This is a highly specific antibody against LIM kinase 1 + 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LIM kinase 1 + 2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
LIMK1 is highly active in the brain and spinal chord, LIMK1 is specifically stimulated by Rac, LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition), Rho and Cdc42, These parts of the brain are important for visualizing an object as a set of parts and performing tasks such as writing, They can phosphorylate an actin-binding protein, and assembling puzzles, cofilin which binds to actin monomers and polymers and promotes the disassembly of actin filament, constructing models, drawing, one of the Rho family proteins, suggesting that two distinct pathways exist in the Rho family driven actin cytoskeleton dynamics, through control of the organization of actin filaments, where it is believed to be involved in the development of nerve cells whilst LIMK2 is ubiquitously expressed in many adult tissues, while LIMK2 activity is activated under the control of other Rho family members, LIMK 1 and 2 likely regulate aspects of the cytoskeleton, The phosphorylation of cofilin via LIMK inactivates this potential |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LIM Enh |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
LIM kinase 1 + 2 |
| Short name: |
LIM kinase 1 + 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, LIM phosphorylation catalyst 1 and 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17468 |
| Gene: |
PDLIM5 |
More about : PDLIM5 |
| Long gene name: |
PDZ and LIM domain 5 |
| Locus: |
4q22, 3 |
| Discovery year: |
2005-01-12 |
| GenBank acession: |
AF061258 |
| Entrez gene record: |
10611 |
| Pubmed identfication: |
15346770 |
| Classification: |
LIM domain containing PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130973 |