| Long name: |
Gbx2 Primary Polyclonal Antibody |
| Also known as: |
Gbx2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Gbx2 |
| Specificity: |
This is a highly specific antibody against Gbx2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gbx2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
DU145 and LNCaP), During development, During development, Furthermore, Gbx2 and Otx2 play distinct, Gbx2 is expressed in the adult brain, Gbx2 negatively regulates Otx2 expression along the anterior-posterior axis, Gbx2(-) mutants demonstrate an expanded Otx2 domain, PC3, Specifically, The GBX2 gene is over-expressed in human prostate cancer cell lines (TSU-prl, The MHB forms at the boundary of expression between homeobox genes Gbx2 and Otx2, downregulation of Gbx2 expression restricts tumorigenicity in human prostate cancer cell lines, essential roles in MHB positioning and development, spleen and female genital tract, the GBX2 gene is expressed in the anterior hindbrain, the GBX2 gene is expressed in the anterior hindbrain, which suggests that Gbx2 expression may be required for growth of malignant prostate cells, The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GBX2_HUMAN, Gastrulation brain homeo box 2, Gastrulation brain homeo box 2 , Homeobox protein GBX 2, Homeobox protein GBX 2 , Homeobox protein GBX-2, Homeobox protein STRA7, Mmoxa, gbx2, Gastrulation and brain-specic homeobox protein 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Gbx2 |
| Short name: |
Gbx2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
gastrulation brain homeobox 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4186 |
| Gene: |
GBX2 |
More about : GBX2 |
| Long gene name: |
gastrulation brain homeobox 2 |
| Synonyms gene name: |
gastrulation brain homeo box 2 |
| Locus: |
2q37, 2 |
| Discovery year: |
1997-10-30 |
| GenBank acession: |
AF118452 |
| Entrez gene record: |
2637 |
| Pubmed identfication: |
9346236 8838315 |
| RefSeq identity: |
NM_001485 |
| Classification: |
HOXL subclass homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000133294 |