| Long name: |
DYRK1A Primary Polyclonal Antibody |
| Also known as: |
DYRK1A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DYRK1A |
| Specificity: |
This is a highly specific antibody against DYRK1A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DYRK1A |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Dyrk family members, Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, Dyrk1A, Dyrk1A is a candidate gene for learning defects that are involved in Downs syndrome (DS), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, Four isoforms of Dyrk1A exist due to alternative splicing events, Localized to the nucleus and highly expressed in testis, Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases, also known as MNB or MNBH, are thought to be involved in diverse cellular functions, functions to phosphorylate serine, including Dyrk1A (dual specificity tyrosine-phosphorylation-regulated kinase 1A), muscle and the developing nervous system, suggesting a possible role for Dyrk1A in the development of DS, threonine and tyrosine residues on various substrates involved in signaling pathways that regulate cell proliferation, which is itself regulated by tyrosine phosphorylation, Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene which is required for neurogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DYR1A_HUMAN, DYRK , DYRK 1, DYRK 1A, DYRK1 , DYRKA, HP 86, HP86, MNB , MNB/DYRK protein kinase antibody, MNBH, Minibrain Drosophila homolog, Minibrain homolog, Protein kinase minibrain homolog, Serine/threonine kinase MNB, Dual specicity tyrosine phosphorylation regulated kinase 1A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DYRK1A |
| Short name: |
DYRK1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DYRK1A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3091 |
| Gene: |
DYRK1A |
More about : DYRK1A |
| Long gene name: |
dual specificity tyrosine phosphorylation regulated kinase 1A |
| Synonyms gene: |
DYRK1 DYRK MNBH |
| Synonyms gene name: |
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| Locus: |
21q22, 13 |
| Discovery year: |
1999-01-29 |
| GenBank acession: |
U52373 |
| Entrez gene record: |
1859 |
| Pubmed identfication: |
9284911 |
| RefSeq identity: |
NM_001396 |
| Havana BLAST/BLAT: |
OTTHUMG00000086657 |