| Long name: |
ALEXA FLUOR 350 Conjugated, RhoA/C Polyclonal Antibody |
| Also known as: |
Anti-RhoA/C PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RhoA/C |
| Specificity: |
This is a highly specific antibody against RhoA/C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
90-140/193 |
| Subcellular location: |
Helical, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RhoA |
| Gene ID Number: |
387, 389 |
| Swiss Prot: |
P61586 |
| Tested applications: |
IF(ICC), IF(IHC-P), FCM |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activated by ARHGEF2, Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly, In turn, Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis, It controls the localization of APC and CLASP2 to the cell membrane, May be an activator of PLCE1, Plays an essential role in cleavage furrow formation, Required for the apical junction formation of keratinocyte cell-cell adhesion, Serves as a target for the yopT cysteine peptidase from Yersinia pestis, Stimulates PKN2 kinase activity, The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex, and Yersinia pseudotuberculosis, membrane-bound APC allows the localization of the MACF1 to the cell membrane, vector of the plague, via the regulation of GSK3B activity, which causes gastrointestinal disorders, which is required for microtubule capture and stabilization, which promotes the exchange of GDP for GTP, Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
ARH12, ARH9, ARHC, RHO12, RHOA, RHOH12, Rho cDNA clone 12, Rho cDNA clone 9, Rho-related GTP-binding protein RhoC, Transforming protein RhoA, h12, ARHA |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
RhoA/C |
| Short name: |
RhoA/C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, ras homolog family member A/C (Antibody to) |
| Alternative technique: |
antibodies |