| Long name: |
FITC Conjugated, OA1/GPR143 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OA1/GPR143 |
| Specificity: |
This is a highly specific antibody against OA1/GPR143 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human OA1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene encoding for OA1 cause ocular albinism, G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation), GPR143, OA1, They respond to a great variety of signaling molecules, also designated ocular albinism type 1 protein (OA1), an X-linked disorder mainly characterized by retinal hypopigmentation and visual impairment, are members of the largest protein family and play a role in many different stimulus-response pathways, including hormones, is a melanosomal protein expressed primarily in pigment cells, is detected exclusively in pigment cells, neurotransmitters and other proteins and peptides, which is a multi-pass membrane protein, G protein-coupled receptors (GPRs or GPCRs) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OA1/GPR143 Conjugated |
| Short name: |
FITC Conjugated, OA1/GPR143 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, OA1/GPR143 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20145 |
| Gene: |
GPR143 |
More about : GPR143 |
| Long gene name: |
G protein-coupled receptor 143 |
| Synonyms gene: |
OA1 |
| Synonyms gene name: |
ocular albinism 1 (Nettleship-Falls) |
| Synonyms name: |
ocular albinism 1 |
| Locus: |
Xp22, 2 |
| Discovery year: |
2003-12-01 |
| GenBank acession: |
Z48804 |
| Entrez gene record: |
4935 |
| Pubmed identfication: |
7647783 10471510 |
| RefSeq identity: |
NM_000273 |
| Classification: |
7TM orphan receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000021118 |
| Locus Specific Databases: |
Albinism Database Mutations of the OA1 Gene |