| Long name: |
Biotin Conjugated, PON3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PON3 |
| Specificity: |
This is a highly specific antibody against PON3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PON3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In contrast to PON1, It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion, PON2 is expressed in a variety of mouse tissues, PON3 is a associated with the high density lipoprotein fraction of serum, PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, Parathion is inert until transformed to paroxon, Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol, The genes which encode PON1-3 are physically linked and map to human chromosome 7q21, including the pancreas, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight, used topically in the treatment of glaucoma, which is expressed mainly in the liver, 3, Paroxon is an organophosphorus anticholinesterase compound |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PON3 Conjugated |
| Short name: |
Conjugated, PON3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PON3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9206 |
| Gene: |
PON3 |
More about : PON3 |
| Long gene name: |
paraoxonase 3 |
| Synonyms name: |
arylesterase 3 |
| Locus: |
7q21, 3 |
| Discovery year: |
1995-05-25 |
| GenBank acession: |
L48516 AF320003 |
| Entrez gene record: |
5446 |
| Pubmed identfication: |
8661009 |
| RefSeq identity: |
NM_000940 |
| Classification: |
Paraoxonases |
| Havana BLAST/BLAT: |
OTTHUMG00000153917 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |