| Long name: |
ZFYVE27 Primary Polyclonal Antibody |
| Also known as: |
ZFYVE27 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ZFYVE27 |
| Specificity: |
This is a highly specific antibody against ZFYVE27 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZFYVE27 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Five isoforms of ZFYVE27 exist as a result of alternative splicing events, Mutations in the gene encoding ZFTVE27 affect neuronal intracellular trafficking in the corticospinal tract and are thought to lead to hereditary spastic paraplegia (HSP), The FYVE domain is a cysteine-rich domain of about 70 amino acids that plays a role in the endosomal localization of the FYVE-finger proteins, ZFYVE27, a multi-pass membrane protein, a neurodegenerative disorder, a protein that is primarily involved in microtubule dynamics and severing, also known as SPG33, and a majority of these proteins serve as regulators of endocytic membrane trafficking, characterized by progressive paralysis of the legs, is a 411 amino acid member of the FYVE-finger family of proteins, is an endosomal protein that binds to Spastin, vesicular trafficking and endosomal trafficking, which is caused by impaired axonal transport, Zinc finger FYVE domain-containing protein 27 (ZFYVE27) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
RP11 459F3, SPG33, ZFY27_HUMAN, ZFYVE27, Zinc finger FYVE domain containing protein 27, Zinc finger FYVE domain-containing protein 27, zinc finger FYVE domain containing 27, 2, Protrudin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ZFYVE27 |
| Short name: |
ZFYVE27 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ZFYVE27 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
26559 |
| Gene: |
ZFYVE27 |
More about : ZFYVE27 |
| Long gene name: |
zinc finger FYVE-type containing 27 |
| Synonyms gene name: |
FYVE domain containing 27 , zinc finger |
| Synonyms: |
FLJ32919 SPG33 |
| Synonyms name: |
protrudin |
| Locus: |
10q24, 2 |
| Discovery year: |
2004-03-05 |
| GenBank acession: |
BC030621 |
| Entrez gene record: |
118813 |
| Pubmed identfication: |
14702039 |
| RefSeq identity: |
NM_144588 |
| Classification: |
Zinc fingers FYVE-type |
| Havana BLAST/BLAT: |
OTTHUMG00000018867 |