Twinkle/ATXN8 Antibody, Cy5.5 Conjugated

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Catalog number: bs-11775R-Cy5.5
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: Twinkle/ATXN8 Antibody, Cy5.5 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy5, 5 Conjugated, Twinkle/ATXN8 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy5, 5, 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Twinkle/ATXN8
Specificity: This is a highly specific antibody against Twinkle/ATXN8
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human Twinkle/ATXN8
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Colocalized with mtDNA (mitochondrial DNA) in mitochondrial nucleoids, Defects in the gene encoding Twinkle are the cause of two conditions: progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant 3 (PEOA3) and sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), PEOA3, PEOA3 is characterized by ptosis and weak muscles, SANDO or TWINL, Twinkle is expressed at high levels in testis, Twinkle is important in the metabolism and maintenance of mtDNA, also known as PEO1 (Progressive external ophthalmoplegia 1 protein), dysarthria and sensory ataxic neuropathies, is a mitochondrial protein that functions as a 5â, nucleotide-dependent DNA helicase, pancreas and skeletal muscle and exists as three isoforms due to alternative splicing events, playing a crucial role in the regulation of mtDNA copy numbers, while SANDO is characterized by ophthalmoparesis, &euro, &euro, &trade, &trade, -3â, Twinkle
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 675nm/694nm
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target: Twinkle/ATXN8 Conjugated
Short name: Conjugated, Twinkle/ATXN8 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: 5, Cy5
Alternative name: cyanine 5, 5 coupled, Twinkle/ATXN8 (Antibody to)
Alternative technique: antibodies
Identity: 32925
Gene: ATXN8 | More about : ATXN8
Long gene name: ataxin 8
Locus: 13q21, 33
Discovery year: 2006-07-18
GenBank acession: DQ641254
Entrez gene record: 724066
Pubmed identfication: 16804541
Classification: Ataxins

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