| Long name: |
ALEXA FLUOR 647 Conjugated, TIMM8A Polyclonal Antibody |
| Also known as: |
Anti-TIMM8A PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TIMM8A |
| Specificity: |
This is a highly specific antibody against TIMM8A |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIMM8A |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in Tim proteins are implicated in several neuro-degenerative diseases, Import of nuclear-encoded precursor proteins into and across the mitochondrial inner membrane is mediated by two distinct complexes, The mitochondrial Tim protein family is comprised of a large group of evolutionarily conserved proteins that are found in most eukaryotes (1, Tim8A and Tim8B, Tim8A is highly expressed in fetal and adult brain (5), Tim8A is mutated in deafness dystonia syndrome, a novel type of disease that causes severe neurological defects, are conserved proteins of the mitochondrial intermembrane space, respectively, suggesting important roles for Tim proteins in development and health (3, the Tim23 complex and the Tim22 complex, thought to be caused by a defective mitochondrial protein transport system (5, which are organized in hetero-oligomeric complex with Tim13 (5, which differ in their substrate specificity (1), which map to human chromosomes Xq22, 1 and 11q23, 1-q23, 2, 2), 4), 6, 7), 8), The majority of mitochondrial-directed proteins are encoded by the nuclear genome and are transported to the mitochondria via regulated processes involving the mitochondrial Tom and Tim proteins (1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
DDP MTS |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TIMM8A Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
TIMM8A |
| Short name: |
TIMM8A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, translocase on inner mitochondrial membrane 8 homolog A (yeast) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, DDP and DDP1 and DFN1 and MTS and TIM8, TIMM8A and IDBG-633444 and ENSBTAG00000022292 and 515109, TIMM8A and IDBG-79593 and ENSG00000126953 and 1678, metal ion binding, this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0006626 and protein targeting to mitochondrion and biological process this GO :0007399 and nervous system development and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0072321 and chaperone-mediated protein transport and biological process, this GO :0046872 : metal ion binding, this GO :0046872 : metal ion binding, translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| Identity: |
11817 |
| Gene: |
TIMM8A |
More about : TIMM8A |
| Long gene name: |
translocase of inner mitochondrial membrane 8A |
| Synonyms gene: |
DFN1 |
| Synonyms gene name: |
translocase of inner mitochondrial membrane 8 (yeast) homolog A translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| Locus: |
Xq22, 1 |
| Discovery year: |
1999-12-01 |
| GenBank acession: |
U66035 |
| Entrez gene record: |
1678 |
| Pubmed identfication: |
10552927 8841189 |
| RefSeq identity: |
NM_004085 |
| Havana BLAST/BLAT: |
OTTHUMG00000022028 |