| Long name: |
Biotin Conjugated, TBCE Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TBCE |
| Specificity: |
This is a highly specific antibody against TBCE |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TBCE |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Biosynthesis of functional microtubules involve the participation of several chaperones, D (TBCD), E (TBCE) and C (TBCC), KCS, KCS1 or pac2, Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1, TBCE (tubulin folding cofactor E), TBCE associates with microtubules and proteasomes, TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network, also known as HRD, alternatively named TCP, and protects against misfolded protein stress, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats, termed Tubulin folding cofactors A (TBCA), that act on folding intermediates downstream of the cytosolic chaperon, the primary component of the cytoskeletal network, Microtubules |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KCS1 pac2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TBCE Conjugated |
| Short name: |
Conjugated, TBCE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TBCE (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11582 |
| Gene: |
TBCE |
More about : TBCE |
| Long gene name: |
tubulin folding cofactor E |
| Synonyms gene: |
KCS HRD |
| Synonyms gene name: |
and dysmorphism , growth and mental retardation, tubulin-specific chaperone e Kenny-Caffey syndrome hypoparathyroidism |
| Locus: |
1q42, 3 |
| Discovery year: |
1998-07-31 |
| GenBank acession: |
U61232 |
| Entrez gene record: |
6905 |
| Pubmed identfication: |
8706133 9806825 12389028 |
| RefSeq identity: |
NM_003193 |
| Havana BLAST/BLAT: |
OTTHUMG00000039987 |