| Long name: |
ALEXA FLUOR 594 Conjugated, TBCE Polyclonal Antibody |
| Also known as: |
Anti-TBCE PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TBCE |
| Specificity: |
This is a highly specific antibody against TBCE |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TBCE |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Biosynthesis of functional microtubules involve the participation of several chaperones, D (TBCD), E (TBCE) and C (TBCC), KCS, KCS1 or pac2, Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1, TBCE (tubulin folding cofactor E), TBCE associates with microtubules and proteasomes, TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network, also known as HRD, alternatively named TCP, and protects against misfolded protein stress, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats, termed Tubulin folding cofactors A (TBCA), that act on folding intermediates downstream of the cytosolic chaperon, the primary component of the cytoskeletal network, Microtubules |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KCS1 pac2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
TBCE |
| Short name: |
TBCE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, TBCE (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11582 |
| Gene: |
TBCE |
More about : TBCE |
| Long gene name: |
tubulin folding cofactor E |
| Synonyms gene: |
KCS HRD |
| Synonyms gene name: |
and dysmorphism , growth and mental retardation, tubulin-specific chaperone e Kenny-Caffey syndrome hypoparathyroidism |
| Locus: |
1q42, 3 |
| Discovery year: |
1998-07-31 |
| GenBank acession: |
U61232 |
| Entrez gene record: |
6905 |
| Pubmed identfication: |
8706133 9806825 12389028 |
| RefSeq identity: |
NM_003193 |
| Havana BLAST/BLAT: |
OTTHUMG00000039987 |