| Long name: |
SMUBP2 Primary Polyclonal Antibody |
| Also known as: |
SMUBP2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SMUBP2 |
| Specificity: |
This is a highly specific antibody against SMUBP2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMUBP2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Belonging to the DNA2/NAM7 helicase family, HMN6 is characterized by weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs and severe respiratory distress, IGHMBP2 also acts as a transcriptional regulator and is necessary for transcriptional activation of the flounder liver-type antifreeze protein gene, IGHMBP2 exists as a homooligomer and is part of the cytosolic ribonucleoprotein complex, IGHMBP2 is a 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction, Mutations in the gene encoding IGHMBP2 are suggested to lead to distal hereditary motor neuronopathy type 6 (HMN6), also known as spinal muscular atrophy distal autosomal recessive 1 (DSMA1) or spinal muscular atrophy with respiratory distress 1 (SMARD1), IGHMBP2 is a 993 amino acid nuclear and cytoplasmic protein that is ubiquitously expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ATP-dependent helicase IGHMBP2, Antreeze enhancer binding protein, CATF 1, CATF1, Cardiac transcription factor 1, Cardiac transcription factor1, DNA-binding protein SMUBP-2, GF-1, Glial factor 1, HCSA, HMN 6, HMN6, IGHMBP 2, Ighmbp2, Immunoglobulin S mu binding protein 2, Immunoglobulin S mu binding protein2, Immunoglobulin mu binding protein 2, Immunoglobulin mu binding protein2, Immunoglobulin mu-binding protein 2, RIPE3 b1, RIPE3b 1, RIPE3b1, SMARD 1, SMARD1, SMBP2_HUMAN, SMUBP 2, AEP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SMUBP2 |
| Short name: |
SMUBP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SMUBP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5542 |
| Gene: |
IGHMBP2 |
More about : IGHMBP2 |
| Long gene name: |
immunoglobulin mu binding protein 2 |
| Synonyms: |
ZFAND7 SMUBP2 CATF1 SMARD1 HCSA HMN6 CMT2S |
| Synonyms name: |
AN1-type domain 7 , cardiac transcription factor 1 zinc finger |
| Locus: |
11q13, 3 |
| Discovery year: |
1994-12-15 |
| GenBank acession: |
L14754 |
| Entrez gene record: |
3508 |
| Pubmed identfication: |
8349627 |
| RefSeq identity: |
NM_002180 |
| Classification: |
UPF1 like RNA helicases Zinc fingers AN1-type |
| Havana BLAST/BLAT: |
OTTHUMG00000167894 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_250 |