| Long name: |
FITC Conjugated, PPP2R2B/PP2A-B55 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PPP2R2B/PP2A-B55 |
| Specificity: |
This is a highly specific antibody against PPP2R2B/PP2A-B55 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A group of proteins that are intimately involved in this process are the protein phosphatases, An additional protein phosphatase catalytic subunit, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity, Four major families of protein phosphatase catalytic subunits have been identified, Gamma and Delta) encoded by four distinct genes, In general, PP2A, PP2A-B55, PP2B (calcineurin) and PP2C, PPX (also known as PP4) is a putative member of a novel PP family, The B family of regulatory subunits (including B55, The PP2A catalytic subunit associates with a variety of regulatory subunits, The PP2A family comprises subfamily members PP2A&, a variable subunit and a catalytic subunit, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, and PP2Aâ, designated PP1, homeostasis and apoptosis, including division, is a B subfamily consisting of four B55 isoforms (Alpha, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, &circ, «, Beta, In eukaryotes, aring |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PR55-BETA PR52B |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PPP2R2B/PP2A-B55 Conjugated |
| Short name: |
FITC Conjugated, PPP2R2B/PP2A-B55 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
b/PP2A-B55 (Antibody to), fluorecein coupled, regulatory functionnal sequence B, protein phosphatase 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
B55BETA and PP2AB55BETA and PP2ABBETA and PP2APR55B and PP2APR55BETA and PR2AB55BETA and PR2ABBETA and PR2APR55BETA and PR52B and PR55-BETA and PR55BETA and SCA12, Cytoplasm, PPP2R2B and IDBG-52116 and ENSG00000156475 and 5521, PPP2R2B and IDBG-646174 and ENSBTAG00000001862 and 509290, Ppp2r2b and IDBG-143462 and ENSMUSG00000024500 and 72930, beta, protein phosphatase type 2A regulator activity, regulatory subunit B, this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008601 and protein phosphatase type 2A regulator activity and molecular function this GO :0050790 and regulation of catalytic activity and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008601 : protein phosphatase type 2A regulator activity, this GO :0008601 : protein phosphatase type 2A regulator activity, protein phosphatase 2 |
| Identity: |
9305 |
| Gene: |
PPP2R2B |
More about : PPP2R2B |
| Long gene name: |
protein phosphatase 2 regulatory subunit Bbeta |
| Synonyms gene: |
SCA12 |
| Synonyms gene name: |
beta isoform , regulatory subunit B (PR 52), spinocerebellar ataxia 12 protein phosphatase 2 (formerly 2A) |
| Synonyms name: |
PP2A subunit B isoform beta |
| Locus: |
5q32 |
| Discovery year: |
1993-01-25 |
| GenBank acession: |
M64930 |
| Entrez gene record: |
5521 |
| Pubmed identfication: |
1849734 10581021 |
| RefSeq identity: |
NM_181678 |
| Classification: |
Protein phosphatase 2 regulatory subunits WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000163381 |